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 Cat.No. KIT 029CE
An ELISA for the determination of oligomerized Mannan-binding lectin (MBL) in human serum or heparin plasma. MBL – a key test in the assessment of primary immunodeficiency Mannan-binding lectin (MBL) is an important component of the innate immune system. However, in at least 12% of the average Caucasian population, the circulating level of functional MBL is insufficient. This makes MBL deficiency by far the most common primary immunodeficiency. Clinical application Deficiency of MBL has been shown to increase the overall susceptibility to infectious diseases and to predispose to greater disease severity; hence especially early and aggressive treatment with antibiotics can be required in risk patients such as those on cancer chemotherapy or immunosuppressant treatment. MBL is a key test parameter in:
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